Protein Details: Gap junction gamma-1 protein

Protein ID

ICDB_Pro_0509

Protein Name

Gap junction gamma-1 protein

Gene Name

GJC1; GJA7

Organism

Homo sapiens (Human)

Length

396 amino acids

AlphaFoldDB

AF-P36383-F1-model_v4.pdb

Function

Sequence

MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQNNPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI

PDB Structures

3SHW

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Heart Disease and Ohdo Syndrome;Sbbys Variant

Location

DOI ID

10.1006/jmcc.1994.1103; 10.1038/ng1285; 10.1038/nature04689; 10.1101/gr.2596504

RefSeq

NP_001073852.1; NP_005488.2; XP_005256977.1; XP_005256978.1